Medical News

Efficacy and safety of Sunitinib in previously treated, advanced non-small cell lung cancer Advanced renal cell carcinoma: efficacy of Lapatinib in patients with high EGFR expression Chronic myeloid leukemia: Dasatinib circumvents Imatinib resistance Esomeprazole reduces gastric ulcers in at-risk patients taking long-term NSAIDs Varenicline can be an effective therapy for smoking cessation Coronary heart disease: transcendental meditation may improve cardiac risk factors Fungal keratitis among soft contact lens wearers Parkin mutations may influence age at onset of Parkinson's disease Erectile dysfunction: Viagra, Cialis and Levitra may be associated with visual loss Hyponatremia associated with SSRI antidepressants in older adults Paroxetine may cause adverse outcomes in neonates when used during pregnancy Cardiovascular risk factors are largely undertreated and undercontrolled in many regions of the world Routine ECGs for newborns would identify long QT syndrome Benefits of Candesartan added to ACE inhibitor in inhibition of progression of nephropathy Advanced breast cancer: Herceptin cardiotoxicity is often reversible Abnormal glucose metabolism may contribute to chronic idiopathic axonal polyneuropathy Implantable defibrillators may increase heart failure risk Stopping antiplatelet drug within 30 days of receiving a drug-eluting stent raises risk of death Diabetes: Genepin reverses some pancreatic dysfunctions Coffee drinking linked to lower risk for alcohol-related liver disease Poor persistence with osteoporosis medications increases fracture risk Fenretinide reduces the risk of second breast cancers in young women Rheumatoid arthritis does not increase risk of hearing loss D-Cycloserine can boost benefits of therapy for social anxiety disorder Drug-induced hepatotoxicity: Acetaminophen, Ketek Cocaine linked to intracerebral hemorrhage in young adults Periconceptional multivitamin use reduces the risk of preeclampsia Regular use of COX-2 inhibitors associated with increased risk for non-Hodgkin lymphoma Nonalcoholic fatty liver disease linked to increased risk of heart disease Onset of psychosis may be delayed by Olanzapine Headache linked to sleep problems in children BRCA1 gene found to control activity of estrogen and progesterone Cancer: SRC3, a powerful promoter of tumor growth Eating more than five portions of fruit and vegetables a day may reduce risk of stroke Reduced brain volume may predict dementia in elderly people Brain abnormality found in Alzheimer's disease related to gait impairment in older persons Effectiveness of Fentanyl lozenges for breakthrough cancer pain Chronic suppurative otits media: topical quinolone antibiotics better than systemic antibiotics HIV infection: ethnic differences in response to HAART Cocoa: Epicatechin has beneficial impact on cardiovascular health Liver cancer: skin rash in patients treated with Lapatinib linked to response to treatment Pancreatic cancer: Gemcitabine added to standard therapy after surgery improves survival Gene therapy protects mice from the effects of whole-body irradiation Weight loss may improve the efficacy of therapy for hepatitis C Overweight and obesity, a cause of cardiac enlargement in adolescents Exercise improves markers of cardiovascular health Calcitriol reduces thrombosis in cancer patients Antibiotics do not prevent recurrent myocardial infarcts in subjects with periodontitis Pharmacogenetics could reduce the incidence of adverse reactions and optimize treatments Side population cells from somites as source of muscle repair cells Parkinson’s disease: utility of the stem cell-derived neurons Oncaspar for newly-diagnosed acute lymphoblastic leukemia Warning of risk to breast cancer patients from vaginal oestrogen LRRK2 gene mutation as major cause of Parkinson's in Ashkenazi Jewish patients HIV infection: Atripla more effective and better tolerated than traditional combination of antiretrovirals Women with endometriosis undergoing IVF benefit from treatment with GnRH agonists Immune system response to viral DNA is unique Pulmonary embolism: a new risk score helps identify patients who are at low risk of death Higher white blood cell count linked to cancer deaths Aspirin may be safe for some survivors of brain hemorrhage Ebola virus infection: antisense drugs protect non-human primates from lethal disease Many patients on diuretics have abnormal sodium and potassium levels Complex infection fighting mechanism described, new light on autoimmune disorders Different factors predispose to chronic fatigue syndrome Obese adolescents: Sibutramine added to behavior therapy reduces BMI and body weight Death in mammalian cells overloaded with saturated fat: role of EF1A-1 protein Age-related macular degeneration may be linked to quality of dietary carbohydrates Chronic myelogenous leukaemia: after five years on Gleevec overall survival reaches 89 percent Dicer enzyme involved in RNA interference CaR essential for localization of blood stem cells Tool to silence genes in specific tissues using RNAi developed miRNA signature in solid tumors identified Genetically engineered muscle-derived stem cells can repair cartilage Statins as potential modifiers of rheumatoid arthritis Avian flu transmission to humans may be higher than thought Depression: brain imaging can predict effectiveness of cognitive behavior therapy 12.5 kDa cystatin could be used to diagnose multiple sclerosis Statin use linked to reduced risk of nuclear cataract NICE and British Hypertension Society: updated clinical guideline on the management of hypertension Hepatotoxicity with black cohosh Interactions with macrolide antibiotics Nerve damage in complex regional pain syndrome-I discovered Soy: no evidence that isoflavones stimulate cell growth in breast tissue Pregnancy: newer antidepressants linked to persistent pulmonary hypertension in newborns Caffeine limits blood flow to heart muscle during exercise Cryopyrin protein responds to invading bacteria by activating of IL-1beta Hedgehog protein blocks fat production, produces more bone Obesity in middle age linked to higher risk of hospitalization and death in older age Atherothrombosis patients often have undertreated, undercontrolled risk factors Inflammation markers identify fatigue in breast cancer survivors Melatonin improves mood in winter depression Exubera: no evidence available of an additional therapeutic benefit Low estrogen levels in men linked to increased risk for hip fracture Vioxx: myocardial infarction can occur within the first two weeks of use All men with erectile dysfunction should be monitored for heart and vascular disease Progeria, a model to explore cardiovascular disease No significant association between levels of physical activity and colon cancer incidence in women Brain cells that produce dopamine depend upon a sex-specific gene Corticosteroids associated with poor outcomes, death in the trauma intensive care unit Stressed-out women more likely to miscarry early Gum-chewing may speed recovery after colon surgery Statins, beta-blockers lessen myocardial infarction risk TNF level predicts who will develop deadly complication after bone marrow transplant Intracerebral hemorrhage: lower doses of tPA safer Anabolic steroids increase myocardial infarction risk and cause liver damage Cystic fibrosis: stopping inhaled corticosteroid use causes no problems Role of gene mutations causing lupus in mice identified Exenatide reduces blood glucose levels when added to patients using a thiazolidinedione Rosuvastatin plus diet in hypercholesterolemic adults unable to tolerate other statins Mechanism for neurodenegerative diseases linked to transport proteins HBZ protein enhances the ability of HTLV-1 to establish a persistent infection ACC/AHA/ESC 2006 Guidelines - Pharmacological rate control during atrial fibrillation Exubera's long-term efficacy and safety in adults with type 1 or type 2 diabetes Trans fat leads to weight gain even on same total calories Inhibition of LDH-A may represent a rational and safe strategy for treatment of cancer Peripheral neuropathic pain: Lyrica is not recommended for use within NHS Scotland Metastatic colorectal cancer - NICE: insufficient evidence to recommend Avastin and Erbitux HIV infection, Prezista, a new protease inhibitor for patients who do not respond to existing drugs, approved Inhibition of TWEAK may provide a new approach to rheumatoid arthritis therapy Region of DNA strongly associated with Alzheimer's disease Combination anti-retroviral therapies associated with reduced infections in HIV-infected children Removal of ovaries decreases risk of ovarian and fallopian tube cancers for women at high-risk Eating fish protects against macular degeneration Antioxidants may help to protect patients with retinitis pigmentosa Nicotine exposure during development leads to hearing problems BNP is a predictor of death in adult sickle cell patients Genetic variation linked to age-related macular degeneration Rho kinase inhibitors cause a fall in the internal anal sphincter tone Cancer stem cells that cause leukemia in a mouse model isolated Sibutramine plus behavior changes helps obese adolescents lose weight Being overweight at age 18 associated with premature death in adulthood Gastric bypass better than gastric banding surgeries in extremely obese patients Enteric anendocrinosis causes chronic diarrhea in children Interaction of proteins in the intestinal system may be allergic indicator Long-term Ibuprofen regimen after brain injury worsens cognition in animal study Psychological stress linked to ovarian tumor growth and spread Prescription analgesics involved in more drug overdose deaths than cocaine or heroin in the US Alterations in GBA gene may contribute to development of dementia with Lewy bodies Weight loss precedes dementia diagnosis in women Proepithelin, a protein key to bladder cancer spread, potential drug target Moderate exercise improves survival rates for colon cancer survivors Hereditary spastic paraplegia linked to REEP1 gene One therapeutic dose of radiation causes 30 percent spongy bone loss in mice People living alone double their risk of acute coronary syndrome High humidity is a risk factor for myocardial infarction deaths among the elderly Retinal vascular calibre may indicate coronary heart death risk New source of multipotent adult stem cells discovered in human hair follicles Higher levels of common daily activity associated with lower risk of death Weight gain may increase risk of breast cancer in postmenopausal women Type 2 diabetes increases the risk of glaucoma in women Link: Medicine News : www.medicinenews.net Xapedia www.xapedia.net www.xapedia.com Xagena: www.xagena.it Progetto Farmaci www.progettofarmaci.it Happy Italy www.happyitaly.net